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Frédéric Veyrier

Areas of expertise

Genomic bacteriology and evolution

450-687-5010 ext. 8831


Armand-Frappier Santé Biotechnologie Research Centre

531 des Prairies Blvd.
Laval, Quebec  H7V 1B7

See the research centre

Research interests

  • Bacterial symbiotes evolution:
  • Bacterial ecology
  • Bacteria-bacteria interactions (bactericidal weapons, molecular shields)
  • Pathogens cell wall


Original research articles

•    Taha MK, Veyrier FJ, Claus H, Lappann M,  Otto A, Becher D, Deghmane AE, Frosch M, Hellenbrand W, Hong E, Parent du Châtelet I, Prior K, Harmsen D, Vogel U. Evolutionary Events Associated with an Outbreak of Meningococcal Disease in Men Who Have Sex with Men. PLoS One (IF: 3.23), 2016 May 11;11(5):e0154047.


•    Veyrier FJ*, Biais N, Morales P., Belkacem N, Guilhen C, Ranjeva S, Sismeiro O, Péhau-Arnaudet G, Rocha EP, Werts C, Taha MK, Boneca IG*. Common cell shape evolution of two nasopharyngeal pathogens. PLoS Genetics(IF: 8.17), 2015 Jul 10;11(7):e1005338.


•    Wang J, McIntosh F, Radomski N, Dewar K, SimeoneR, Enninga J, BroschR, RochaEP, VeyrierFJ* & Behr MA*. Insights on the emergence of Mycobacterium tuberculosisfrom the analysis of Mycobacterium kansasii. Genome Biology and Evolution. (IF : 4.53) 2015 Feb 25;7(3):856-70.


•    Ratet G, Veyrier FJ, Fanton d’Andon M, Kammerscheit X, Nicola MA, Picardeau M, Werts C*. Live imaging of bioluminescent Leptospira interrogans in mice reveals renal colonization as a stealth escape from the immune response and antibiotics. PLoS Negl Trop Dis. 2014 Dec 4;8(12):e3359. doi: 10.1371/journal.pntd.0003359.


•    Williams AH, Veyrier FJ, Bonis M, Michaud Y, Raynal B, Taha MK, Haouz A & Boneca IG*. Visualization of a substrate-induced catalytic triad of the Neisseria meningitidis peptidoglycan O-acetylesterase reveals mechanistic conservation in the SGNH esterase family member. Acta Crystallogr D Biol Crystallogr. 2014, Oct;70(Pt 10):2631-9. doi: 10.1107/S1399004714016770.


•    Radomski N, Roguet A, Lucas FS, Veyrier FJ, Cambau E, Accrombessi H, Moilleron R, Behr MA & Moulin L*. atpE gene as a new useful specific molecular target to quantify Mycobacterium in environmental samples.  BMC microbiology, 2013, Dec 3;13:277.


•    Veyrier FJ,  Ecobichon C, Boneca IG*. Draft Genome Sequence of Helicobacter pylori X47-2AL. Genome announc, 2013, Dec 19;1(6). pii: e01095-13.


•    Veyrier FJ*, Hong E, Deghmane AE, Taha MK*. Draft Genome Sequence of a Neisseria meningitidis Serogroup C Isolate of Sequence Type 11 Linked to an Outbreak among Men Who Have Sex with Men. Genome announc, 2013, Oct 3;1(5). pii: e00795-13.


•    Hansen JM, Golchin SA, Veyrier FJ, Domenech P, Boneca IG, Azad AK, Rajaram MVS, Schlesinger LS, Divangahi M, Reed MB & Behr MA*. N-glycolylated peptidoglycan contributes to the immunogenicity but not pathogenicity of Mycobacterium tuberculosis. J Infect Dis, 2013, Dec 19. [Epub ahead of print]


•    Veyrier FJ*, Williams A, Mesnage S, Schmitt C, Taha MK & Boneca IG*. De-O-acetylation of peptidoglycan regulates glycan chain extension and affects in vivo survival of Neisseria meningitidis. Mol Microbiol, 2013, Mar;87(5):1100-12.


•    Hong E, Hedberg ST, Abad R, Fazio C, Enríquez R, Deghmane AE, Jolley KA, Stefanelli P, Unemo M, Vazquez J, Veyrier FJ & Taha MK*. Target gene (gyrA, parC and parE) sequencing to define the susceptibility of Neisseria meningitidis to ciprofloxacin. Antimicrob Agents Chemother, 2013, Apr;57(4):1961-4.


•    Veyrier FJ*, Boneca IG, Cellier MF & Taha MK. Manganese export, via a new family of metallo-transporters, is positively selected to regulate the Mn/Fe intracellular ratio in N. meningitidis. PLOS Pathog, 2011, 7:e1002261


•    Veyrier F, Pletzer D, Turenne C & Behr MA*. Phylogenetic detection of horizontal gene transfer during the step-wise genesis of Mycobacterium tuberculosis. BMC Evol Biol, 2009, 9:196


•    Coulombe F, Divangahi M, Veyrier FJ, de Léséleuc L, Gleason J, Yang Y, Kelliher MA, Pandey AK, Sassetti CM, Reed MB & Behr MA*. Increased NOD2-mediated recognition of N-glycolyl muramyl dipetide. J Exp Med, 2009, 206:1709-16


•    Divangahi M, Coulombe F, Mostowy S, Kosak R, Veyrier F, Guillot L, Reed MB, Gleason J, Kobayashi KS, Flavell RA, Gros P & Behr MA*. NOD2-deficient mice have impaired resistance to Mycobacterium tuberculosis infection through defective innate and adaptive immunity. J Immunol, 2008, 181:7157-65


•    Veyrier F, Said-Salim B & Berh MA*. Evolution of the mycobacterial SigK regulon. J Bacteriol, 2008, 190:1891-9


•    Chaloupka R, Courville P, Veyrier F, Knudsen B, Tompkins TA & Cellier MF*. Identification of essential amino acids in the Nramp family by a combination of evolutionary analysis and biophysical studies of metal and proton co-transport in vivo. Biochemistry, 2005, 44:726-33


•    Courville P, Chaloupka R, Veyrier F & Cellier MF*. Determination of transmembrane topology of the Escherichia coli natural resistance-associated macrophage protein (Nramp) ortholog. J Biol Chem, 2004, 279:3318-26




•    Chen NH, Djoko KY, Veyrier FJ, McEwan AG. Formaldehyde Stress Responses in Bacterial Pathogens. Front Microbiol. 2016 Mar 3;7:257.


•    Veyrier FJ* & Cellier MF*. Metal economy in host-microbe interactions. Front Cell Infect Microbiol, 2015, 4:190, 10.3389/fcimb.2014.00190. eCollection 2014.


•    Guilhen C, Taha MK & Veyrier FJ*. Role of transition metal exporters in virulence: the example of Neisseria meningitidis. Front Cell Infect Microbiol, 2013, 10.3389/fcimb.2013.00102


•    Veyrier FJ, Dufort A & Behr MA*. The rise and fall of the Mycobacterium tuberculosis genome. Trends Microbiol, 2011, 19:156-61



Book chapters

•    Wheeler R, Veyrier FJ, Werts C, Boneca IG*. Peptidoglycan and Nod receptors.  Glycoscience: Biology and Medicine, Springer