Confocal Microscopy and Flux Cytometry Laboratory

The Confocal Microscopy and Flux Cytometry Laboratory allows scientists to conduct cutting edge research in cellular and molecular biology, including real-time observation and study of cellular and subcellular interactions involved in the transmission of bacterial, parasitic, and viral diseases.

The Confocal Microscopy and Flux Cytometry Laboratory plays an important role for the scientific community of INRS’s Armand-Frappier Santé Biotechnologie Research Centre. It serves over 65 users from some 20 laboratories.

The facility allows research teams to study the mechanisms of macrophage activation, a prerequisite for the development of new pharmacological approaches based on the selective manipulation of macrophage intracellular signaling pathways to stimulate the immune system. Their research also looks at the interaction between the Leishmania parasite and the macrophage at the cellular and molecular levels, and on the virulence spectra of this parasite, in order to combat leishmaniasis, which affects 12 million people a year.

The Confocal Microscopy and Flux Cytometry Laboratory is equipped with:

  • A four-laser BD LSRFortessa cytometer for high-level multiparametric analyses to characterize cell populations
  • Atwo-laser BD FACS Calibur for conducting routine analyses such as of surface marker expression
  • A Zeiss LSM780 confocal microscopy system, a state-of-the-art instrument for the study of various biological processes at the cellular and subcellular levels, such as intracellular trafficking and pathogen molecule localization

The acquisition of this facility in 2012 was made possible by a $210,000 donation from the Armand-Frappier Foundation and a grant of over $750,000 from Ministère de l’Économie et de l’Innovation as part of the Research Support Program – Component 2.

Contacts

Albert Descoteaux
Professor and Scientific leader
Phone: 450-686-5010
Email: albert.descoteaux@iaf.inrs.ca

Jessy Tremblay
Terms of Use and Pricing
Phone: 450-687-5010 extension 4314
Email: jessy.tremblay@iaf.inrs.ca

Confocal Microscopy and Flux Cytometry Laboratory

Institut national de la recherche scientifique 

Armand-Frappier Santé Biotechnologie Research Centre

531 blvd. des Prairies

Laval, Quebec  H7V 1B7

Canada

Voir sur la carte