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Marc A Gauthier

Recherche étudiant·es ou stagiaires

Expertises

Chimie dynamique, chimie bioorganique et biomatériaux

Téléphone
514 228-6932 

Courriel
marc.andre.gauthier@inrs.ca 

Centre Énergie Matériaux Télécommunications

Notre laboratoire se situe sur le Campus Laval de l’INRS au: 

531, boulevard des Prairies, Bâtiment 70, Laval (Québec)  H7V 1B7 Canada 

Rejoignable depuis Montreal via le bus/métro/voiture 

Localisation précise de notre laboratoire (même bâtiment que le Centre Québécois d’Innovation en Biotechnologie; CQIB). 

Voir le centre

Intérêts de recherche

Nous sommes intéressés par la recherche académique, les partenariats académie–industrie, la recherche contractuelle, la consultation scientifique et la prestation de services analytiques dans les domaines suivants : 

Bioconjugués & Agents Thérapeutiques 

  • Bioconjugués thérapeutiques (peptides, protéines, acides nucléiques, polymères, etc.) 
  • Conjugaison polymère–protéine (PEGylation, PEGylation réversible, linkers), fluorophore–protéine, etc.
  • Revêtements à tamis moléculaire (revêtements immunoprotecteurs) 
  • Biophysique des bioconjugués (mécanismes d’inactivation, prédictions de propriétés in silico) 
  • Repliement de peptides multi-cycliques (appariement contrôlé des ponts disulfure) 
  • Production et analyse de bioconjugués 
  • Bioconjugués sensibles aux stimuli (pH, redox, stress oxydatif) 
  • Thérapies enzymatiques 

Articles de revue: Chem Commun 2008 (review);

Nanotechnologie ADN & Ingénierie Moléculaire 

  • Nanostructures ADN, nanotechnologie ADN, interrupteurs ADN 
  • Biomatériaux sensibles aux micro-ondes / radiofréquences 
  • Piégeurs d’amyloïdes basés sur l’ADN 
  • Plateforme de criblage d’anticorps multi-spécifiques (bi-spécifiques, tri-spécifiques, etc.) 
  • Biocapteurs ADN–graphène, biodétection 


Chimie Covalente Dynamique & Modification Sélective des Résidus
 

  • Conjugaison sélective des résidus cystéine, méthionine et arginine 
  • Bioconjugaison covalente réversible 
  • « Linkers » réactifs 


Caractérisation Biophysique & Mécanistique
 

  • Développement d’assays (bio)analytiques complexes 
  • Effets tampons de polymères à l’échelle nanométrique 
  • Phénomènes de volume exclu et d’encombrement moléculaire 


Stratégies Antimicrobiennes & Antivirales
 

  • Inactivation virale induite par laser 
  • Surfaces auto-assainissantes nanostructurées 

Projets d’études ou stages offerts

Publications

Title Cited by Year
Detection of Obliterated Traceability Elements in Polypropylene through Strain-Induced Photoluminescence Variations

L Skokan, Y González, D Gueckelhorn, MA Gauthier, C Muehlethaler, …

Analytical Chemistry 98 (7), 5344-5352

2026
A General Approach to Predict and Tailor the Nanoscale Permeability of Comb‐Shaped Polymer Coatings

N Drossis, MA Gauthier, HW de Haan

Small Methods 9 (7), 2500140

2025
A Hybrid Molecule/Graphene van der Waals Heterostructure for DNA Immobilization and Detection

Z Yang, AA Greschner, L Skokan, A Ruediger, O Sedlacek, …

Nano Letters 25 (22), 8884-8891

1 2025
Direct quantification of PEGylation for intact bioconjugates and nanoparticles by the colorimetric barium/iodide assay

K Coutu, A Ngabonziza Sangwa, N Gaudreault, SS Tayebi, T Hoare, …

Biomacromolecules 26 (6), 3689-3699

2 2025
Void engineering to promote the self-cleaning properties of bactericidal zinc oxide nanopillar array coatings

A Hassanpour, MC Groleau, D Messaoudi, AA Greschner, K Kohlmann, …

Materials Advances 6 (14), 4687-4695

1 2025
Preclinical validation of human recombinant glutamate-oxaloacetate transaminase for the treatment of acute ischemic stroke

M Pérez-Mato, A Dopico-López, Y Akkoc, S López-Amoedo, …

Iscience 27 (11)

5 2024
Rapid Systematic Screening of Bispecific Antibody Surrogate Geometries for T-Cell Engagement Using DNA Nanotechnology

S Messaoudi, K Wai, A Marple, SF Baniahmad, RG Wylie, M Pelletier, …

Journal of the American Chemical Society 146 (43), 29824-29835

4 2024
Stability of a multiresponsive sulfonium vinyl sulfide linker toward nucleophilic/radical thiols, reactive nitrogen species, and in cells under pro-inflammatory stimulation

F Zare, P Laplante, AA Greschner, JF Cailhier, MA Gauthier

Biomacromolecules 25 (9), 6017-6025

3 2024
Harnessing Water Competition to Drive Enzyme Crosstalk

A Meziadi, V Bloquert, AA Greschner, HW de Haan, MA Gauthier

Biomacromolecules 25 (9), 6072-6081

2024
Synthetic peptide shuttle agent bioconjugates for intracellular cargo delivery

AH SOULTAN, D Guay, JP LEPETIT-STOFFAES, T DEL’GUIDICE, …

US Patent App. 18/553,178

2 2024
DNA nanostructures prevent the formation of and convert toxic amyloid proteospecies into cytocompatible and biodegradable spherical complexes

N Kihal, PT Nguyen, A Nazemi, AA Greschner, MA Gauthier, S Bourgault

Aggregate 5 (3), e502

11 2024
Ion-retention properties of graphene oxide/zinc oxide nanocomposite membranes at various pH and temperature conditions

A Hassanpour, MA Gauthier, S Sun

Scientific Reports 14 (1), 1443

5 2024
Nanoporcupine, method of manufacture and use thereof

A HASSANPOUR, MA GAUTHIER, S Sun, MC GROLEAU, E Deziel

US Patent App. 18/312,665

1 2023
PEGylation of a peptide-based amphiphilic delivery agent and influence on protein delivery to cells

AA Greschner, N Brahiti, M Auger, L Hu, H Soleymani Abyaneh, …

Biomacromolecules 24 (11), 4890-4900

15 2023
Correction to “Consecutive Alkylation,“Click”, and “Clip” Reactions for the Traceless Methionine-Based Conjugation and Release of Methionine-Containing Peptides”

F Zare, A Potenza, AA Greschner, MA Gauthier

Biomacromolecules 24 (6), 2955-2956

2023
Microwave-Induced Transient Heating Accelerates Protein PEGylation

A Meziadi, AA Greschner, MA Gauthier

Biomacromolecules 24 (6), 2856-2863

1 2023
Overcoming PEG─ Protein Mutual Repulsion to Improve the Efficiency of PEGylation

A Meziadi, N Zuberi, HW de Haan, MA Gauthier

Biomacromolecules 23 (11), 4948-4956

6 2022
Consecutive Alkylation,“Click”, and “Clip” Reactions for the Traceless Methionine-Based Conjugation and Release of Methionine-Containing Peptides

F Zare, A Potenza, AA Greschner, MA Gauthier

Biomacromolecules 23 (7), 2891-2899

6 2022
Elucidating the mechanisms of the molecular sieving phenomenon created by comb-shaped polymers grafted to a protein–a simulation study

N Drossis, MA Gauthier, HW de Haan

Materials Today Chemistry 24, 100861

9 2022
Aqueous Zn‐based rechargeable batteries: recent progress and future perspectives

M Wu, G Zhang, H Yang, X Liu, M Dubois, MA Gauthier, S Sun

InfoMat 4 (5), e12265

173 2022
New perspectives for developing therapeutic bioconjugates of metabolite-depleting enzymes: Lessons learned combating glutamate excitotoxicity

A Zaghmi, M Perez-Mato, A Dopico-López, M Candamo-Lourido, …

Biomacromolecules 23 (5), 1864-1872

9 2022
Noninvasive, label‐free, and quantitative monitoring of lipase kinetics using terahertz emission technology

S Nahar, A Mohamed, X Ropagnol, A Hassanpour, T Kiwa, T Ozaki, …

Biotechnology and Bioengineering 118 (11), 4246-4254

6 2021
Nanostructured metal borides for energy‐related electrocatalysis: recent progress, challenges, and perspectives

Z Pu, T Liu, G Zhang, X Liu, MA Gauthier, Z Chen, S Sun

Small Methods 5 (10), 2100699

96 2021
Treating brain diseases using systemic parenterally-administered protein therapeutics: Dysfunction of the brain barriers and potential strategies

A Zaghmi, J Drouin-Ouellet, D Brambilla, MA Gauthier

Biomaterials 269, 120461

18 2021
Sustained blood glutamate scavenging enhances protection in ischemic stroke

A Zaghmi, A Dopico-López, M Pérez-Mato, R Iglesias-Rey, P Hervella, …

Communications biology 3 (1), 729

34 2020
Comparative study on the inactivation of MS2 and M13 bacteriophages using energetic femtosecond lasers

A Berchtikou, E Sokullu, S Nahar, P Tijssen, MA Gauthier, T Ozaki

Journal of Biophotonics 13 (10), e202000109

5 2020
Plasmonic enhancement of two-photon excitation fluorescence by colloidal assemblies of very small AuNPs templated on M13 phage

E Sokullu, M Pinsard, J Zhang, J Plathier, G Kolhatkar, AS Blum, F Légaré, …

Biomacromolecules 21 (7), 2705-2713

8 2020
The phage display of Bacillus subtilis Lipase A significantly enhances catalytic activity due to altered nanoscale distribution in colloidal solution

S Nahar, E Sokullu, MA Gauthier

Biotechnology and bioengineering 117 (3), 868-872

6 2020
Cascaded optical polymer waveguide for enhanced fluorescence evanescent wave spectroscopy

J Abdul-Hadi, MA Gauthier, M Packirisamy

Optics & Laser Technology 123, 105904

4 2020
Photocatalytic interlayer spacing adjustment of a graphene oxide/zinc oxide hybrid membrane for efficient water filtration

A Hassanpour, S Nahar, X Tong, G Zhang, MA Gauthier, S Sun

Desalination 475, 114174

41 2020
Accelerated inactivation of M13 bacteriophage using millijoule femtosecond lasers

A Berchtikou, AA Greschner, P Tijssen, MA Gauthier, T Ozaki

Journal of Biophotonics 13 (2), e201900001

10 2020
Towards extracellular matrix normalization for improved treatment of solid tumors

HS Abyaneh, M Regenold, TD McKee, C Allen, MA Gauthier

Theranostics 10 (4), 1960

122 2020
Surface vs. core N/S/Se-heteroatom doping of carbon nanodots produces divergent yet consistent optical responses to reactive oxygen species

X Geng, TR Congdon, P Anees, AA Greschner, F Vetrone, MA Gauthier

Nanoscale Advances 2 (9), 4024-4033

5 2020
In vivo properties of therapeutic bioconjugates composed of proteins and architecturally/functionally complex polymers

A Zaghmi, AA Greschner, MA Gauthier

Polymer-Protein Conjugates, 389-406

5 2020
Homogenous Scavenging Resolves Low-Purification Yield/Selectivity Caused by Secondary Binding of Protein-A to Antigen-Binding Antibody Fragments

P Anees, MA Gauthier

Biomacromolecules 21 (2), 825-829

2 2019
Progress toward absorption, distribution, metabolism, elimination, and toxicity of DNA nanostructures

S Messaoudi, AA Greschner, MA Gauthier

Advanced Therapeutics 2 (12), 1900144

21 2019
Ultra-sub-stoichiometric “Dynamic” Bioconjugation Reduces Viscosity by Disrupting Immunoglobulin Oligomerization

Y Gong, H Soleymani Abyaneh, N Drossis, A Niederquell, M Kuentz, …

Biomacromolecules 20 (9), 3557-3565

4 2019
Determination of the degree of PEGylation of protein bioconjugates using data from proton nuclear magnetic resonance spectroscopy

A Zaghmi, AA Greschner, E Mendez-Villuendas, JY Liu, HW de Haan, …

Data in brief 25, 104037

14 2019
Mechanisms of activity loss for a multi-PEGylated protein by experiment and simulation

A Zaghmi, E Mendez-Villuendas, AA Greschner, JY Liu, HW De Haan, …

Materials Today Chemistry 12, 121-131

62 2019
Plant/bacterial virus-based drug discovery, drug delivery, and therapeutics

E Sokullu, H Soleymani Abyaneh, MA Gauthier

Pharmaceutics 11 (5), 211

60 2019
Chemical vapour deposition of graphene: Layer control, the transfer process, characterisation, and related applications

X Yang, G Zhang, J Prakash, Z Chen, M Gauthier, S Sun

International Reviews in Physical Chemistry 38 (2), 149-199

74 2019
Bio-conjugate approaches to mAb manufacturing

A Palapuravan, Y Gong, H Soleymani, Y Zhao, A Greschner, T Congdon, …

ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 257

2019
Room-temperature and selective triggering of supramolecular DNA assembly/disassembly by nonionizing radiation

AA Greschner, X Ropagnol, M Kort, N Zuberi, J Perreault, L Razzari, …

Journal of the American Chemical Society 141 (8), 3456-3469

50 2019
Ultra-sub-stoichiometric

Y Gong, N Drossis, A Niederquell, M Kuentz, JC Leroux, HW de Haan, …

Biomacromolecules

2019
Precise orientation of thermally-sensitive biomolecules using DNA nanostructures: An exploration of non-thermal techniques for controlling DNA nanoassemblies

A Greschner, X Ropagnol, M Kort, N Zuberi, J Perreault, L Razzari, …

JACS 141 (8), 3456-3469

2019
Evidence, manipulation, and termination of pH ‘Nanobuffering’for quantitative homogenous scavenging of monoclonal antibodies

P Anees, Y Zhao, AA Greschner, TR Congdon, HW de Haan, N Cottenye, …

ACS nano 13 (2), 1019-1028

24 2018
Polymer on quartz waveguide sensing platform for enhanced evanescent fluorescence spectroscopy

J Abdul-Hadi, MA Gauthier, M Packirisamy

IEEE Photonics Journal 10 (6), 1-15

6 2018
Ferroelectric tunnel junction and method of fabrication thereof

A Ruediger, F Ambriz-Vargas, G Kolhatkar, R Thomas, AH Youssef, …

US Patent 10,056,394

2 2018
Silicon-free, low-loss and high contrast polymer multimode waveguides

J Abdul-Hadi, MA Gauthier, M Packirisamy

Journal of Micromechanics and Microengineering 27 (10), 105006

6 2017
Stimuli-responsive protein-polymer conjugates for bioseparation

C Kent, W Baille, M Gauthier, Y Zhao, N COTTENYE

US Patent App. 15/515,936

4 2017
Extreme nonlinear carrier dynamics induced by intense quasi-half-cycle THz pulses in n-doped InGaAs thin film

X Chai, X Ropagnol, M Raeiszadeh, S Safavi-Naeini, M Reid, …

CLEO: QELS_Fundamental Science, FW1H. 3

2 2017
A complementary metal oxide semiconductor process-compatible ferroelectric tunnel junction

F Ambriz-Vargas, G Kolhatkar, M Broyer, A Hadj-Youssef, R Nouar, …

ACS applied materials & interfaces 9 (15), 13262-13268

231 2017
Tunneling electroresistance effect in a Pt/Hf0. 5Zr0. 5O2/Pt structure

F Ambriz-Vargas, G Kolhatkar, R Thomas, R Nouar, A Sarkissian, …

Applied Physics Letters 110 (9)

144 2017
Influence of gap size on intense THz generation from ZnSe interdigitated large aperture photoconductive antennas (October 2016)

X Ropagnol, X Chai, SM Raeis-Zadeh, S Safavi-Naeini, M Kirouac-Turmel, …

IEEE Journal of Selected Topics in Quantum Electronics 23 (4), 1-8

8 2017
RF-magnetron sputtering deposition of ultra-thin Hf0. 5Zr0. 5O2 films for non-volatile memory applications

F Ambriz-Vargas, R Nouar, G Kolhatkar, A Sarkissian, R Thomas, …

Materials Today: Proceedings 4 (7), 7000-7010

6 2017
Synthesis and characterization of thin-transparent nanostructured films for surface protection

S Veltri, E Sokullu, M Barberio, MA Gauthier, P Antici

Superlattices and Microstructures 101, 209-218

9 2017
Releasable and traceless PEGylation of arginine-rich antimicrobial peptides

Y Gong, D Andina, S Nahar, JC Leroux, MA Gauthier

Chemical science 8 (5), 4082-4086

53 2017
In vitro and in vivo evaluation of PEGylated layer‐by‐layer polyelectrolyte‐coated paclitaxel nanocrystals

A Polomska, MA Gauthier, JC Leroux

Small 13 (2), 1602066

43 2017
Nonlinear ultrafast terahertz waveform modulation in highly n-doped In0.53Ga0.47As thin film

X Chai, X Ropagnol, M Raeiszadeh, S Safavi-Naeini, M Reid, …

2016 41st International Conference on Infrared, Millimeter, and Terahertz …

2016
Asymmetric half-cycle THz pulses with large ponderomotive potential generated from photoconductive antennas

X Ropagnol, M Raeiszadeh, S Safavi-Naeini, M Reid, MA Gauthier, …

2016 41st International Conference on Infrared, Millimeter, and Terahertz …

1 2016
P1‐076: Development of Bio‐Conjugates for the Treatment of Excitotoxicity During Alzheimer’s Disease

A Zaghmi, A Greschner, MA Gauthier, C Ramassamy

Alzheimer’s & Dementia 12, P431-P431

2016
Dependence of intense THz generation on gap size from ZnSe interdigitated large aperture photoconductive antennas

X Ropagnol, SM Raeis-Zadeh, S Safavi-Naeini, M Bouvier, CY Côté, …

CLEO: Applications and Technology, JTh2A. 64

2 2016
Intense THz pulses with large ponderomotive potential generated from large aperture photoconductive antennas

X Ropagnol, M Khorasaninejad, M Raeiszadeh, S Safavi-Naeini, …

Optics express 24 (11), 11299-11311

77 2016
Biomedical applications of polymers made from natural compounds

Y Jia, K Wang, F Le Devedec, S Strandman, MA Gauthier, JE Gautrot, …

ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 251

2016
Correction: Corrigendum: Sustained gastrointestinal activity of dendronized polymer–enzyme conjugates

G Fuhrmann, A Grotzky, R Lukić, S Matoori, P Luciani, H Yu, B Zhang, …

Nature Chemistry 8 (3), 281-281

2016
PEG-Enzyme for neurodegenerative diseases treatment

A Zaghmi, A Greschner, C Ramassamy, MA Gauthier

2016
Les bio-conjugues pour le traitement de la maladie d’Alzheimer

A Zaghmi, A Greschner, C Ramassamy, MA Gauthier

2016
Nano-engineered electro-responsive drug delivery systems

Y Zhao, AC Tavares, MA Gauthier

Journal of Materials Chemistry B 4 (18), 3019-3030

105 2016
Preparation and characterization of nanostructured films: study of hydrophobicity and antibacterial properties for surface protection

M Barberio, S Veltri, E Sokullu, F Xu, MA Gauthier, P Antici

Advanced Processing and Manufacturing Technologies for Nanostructured and …

1 2015
Site-Specific Polymer Conjugation Stabilizes Therapeutic Enzymes in the Gastrointestinal Tract.

JD Schulz, M Patt, S Basler, H Kries, D Hilvert, MA Gauthier, JC Leroux

Advanced materials (Deerfield Beach, Fla.) 28 (7), 1455-1460

49 2015
Improving oral drug bioavailability with polycations?

JD Schulz, MA Gauthier, JC Leroux

European Journal of Pharmaceutics and Biopharmaceutics 97, 427-437

50 2015
Conformation–function relationships for the comb-shaped polymer pOEGMA

M Liu, JC Leroux, MA Gauthier

Progress in polymer science 48, 111-121

83 2015
The interplay of disulfide bonds, α-helicity, and hydrophobic interactions leads to ultrahigh proteolytic stability of peptides

Y Chen, C Yang, T Li, M Zhang, Y Liu, MA Gauthier, Y Zhao, C Wu

Biomacromolecules 16 (8), 2347-2355

33 2015
Releasable conjugation of polymers to proteins

Y Gong, JC Leroux, MA Gauthier

Bioconjugate chemistry 26 (7), 1172-1181

88 2015
Generation of elliptically polarized half-cycle terahertz pulses generated by 6H-SiC large aperture photoconductive antenna

X Ropagnol, M Bouvier, CY Côté, M Reid, MA Gauthier, T Ozaki

2015 Conference on Lasers and Electro-Optics (CLEO), 1-2

1 2015
Twin disulfides as opportunity for improving stability and transfection efficiency of oligoaminoethane polyplexes

PM Klein, K Müller, C Gutmann, P Kos, AK Levacic, D Edinger, M Höhn, …

Journal of Controlled Release 205, 109-119

53 2015
Disulfide-containing parenteral delivery systems and their redox-biological fate

L Brülisauer, MA Gauthier, JC Leroux

Journal of Controlled Release 195, 147-154

232 2014
Semi-permeable coatings fabricated from comb-polymers efficiently protect proteins in vivo

M Liu, P Johansen, F Zabel, JC Leroux, MA Gauthier

Nature communications 5 (1), 5526

81 2014
Bio‐reduction of Redox‐Sensitive Albumin Conjugates in FcRn‐Expressing Cells

L Brülisauer, G Valentino, S Morinaga, K Cam, J Thostrup Bukrinski, …

Angewandte Chemie 126 (32), 8532-8536

21 2014
Redox-responsive drug delivery

MA Gauthier

Antioxidants & redox signaling 21 (5), 705-706

31 2014
Targeting of injectable drug nanocrystals

K Fuhrmann, MA Gauthier, JC Leroux

Molecular pharmaceutics 11 (6), 1762-1771

87 2014
Complex single-chain polymer topologies locked by positionable twin disulfide cyclic bridges

O Shishkan, M Zamfir, MA Gauthier, HG Börner, JF Lutz

Chemical Communications 50 (13), 1570-1572

63 2014
Modular design of redox-responsive stabilizers for nanocrystals

K Fuhrmann, A Połomska, C Aeberli, B Castagner, MA Gauthier, …

ACS nano 7 (9), 8243-8250

68 2013
Polymer–Enzyme Conjugates for Oral Drug Delivery Applications: Polymer and Colloid Highlights

G Fuhrmann, MA Gauthier, JC Leroux

Chimia 67 (9), 685-685

1 2013
Broad control of disulfide stability through microenvironmental effects and analysis in complex redox environments

C Wu, S Wang, L Brülisauer, JC Leroux, MA Gauthier

Biomacromolecules 14 (7), 2383-2388

49 2013
Sustained gastrointestinal activity of dendronized polymer–enzyme conjugates

G Fuhrmann, A Grotzky, R Lukić, S Matoori, P Luciani, H Yu, B Zhang, …

Nature chemistry 5 (7), 582-589

125 2013
Molecular sieving on the surface of a protein provides protection without loss of activity

M Liu, P Tirino, M Radivojevic, DJ Phillips, MI Gibson, JC Leroux, …

Advanced Functional Materials 23 (16), 2007-2015

62 2013
New methacrylic monomers for dental applications

K Zhang, W Baille, M Gauthier, XX Zhu, S Lerouge, D Fortin

2013
Twin disulfides for orthogonal disulfide pairing and the directed folding of multicyclic peptides

C Wu, JC Leroux, MA Gauthier

Nature chemistry 4 (12), 1044-1049

86 2012
Tracking the bioreduction of disulfide-containing cationic dendrimers.

L Brülisauer, N Kathriner, M Prenrecaj, MA Gauthier, JC Leroux

Angewandte Chemie (International ed. in English) 51 (50), 12454-12458

80 2012
Lipase Is Essential for the Study of in Vitro Release Kinetics from Organogels

MH Dufresne, E Marouf, Y Kränzlin, MA Gauthier, JC Leroux

Molecular pharmaceutics 9 (6), 1803-1811

14 2012
PEG nanocages as non-sheddable stabilizers for drug nanocrystals

K Fuhrmann, JD Schulz, MA Gauthier, JC Leroux

ACS nano 6 (2), 1667-1676

76 2012
New pharmaceutical applications for macromolecular binders

N Bertrand, MA Gauthier, C Bouvet, P Moreau, A Petitjean, JC Leroux, …

Journal of controlled release 155 (2), 200-210

56 2011
Interplay of chemical microenvironment and redox environment on thiol–disulfide exchange kinetics

C Wu, C Belenda, JC Leroux, MA Gauthier

Chemistry–A European Journal 17 (36), 10064-10070

86 2011
Arginine-specific modification of proteins with polyethylene glycol

MA Gauthier, HA Klok

Biomacromolecules 12 (2), 482-493

98 2011
Methacrylate derivatives of bile acids for use as monomers for dental resins

MA Gauthier, S Lerouge, D Fortin, XX Zhu

2011
Arginine-specific protein modification using α-oxo-aldehyde functional polymers prepared by atom transfer radical polymerization

MA Gauthier, M Ayer, J Kowal, FR Wurm, HA Klok

Polymer Chemistry 2 (7), 1490-1498

18 2011
Crosslinkable polymers for nanocrystal stabilization

K Fuhrmann, MA Gauthier, JC Leroux

Journal of Controlled Release 148 (1), e12-e13

12 2010
Polymer Chemistry

MA Gauthier, C Zhao

1 2010
Polymer–protein conjugates: an enzymatic activity perspective

MA Gauthier, HA Klok

Polymer chemistry 1 (9), 1352-1373

208 2010
New dental composites containing multimethacrylate derivatives of bile acids: a comparative study with commercial monomers

MA Gauthier, Z Zhang, XX Zhu

ACS Applied Materials & Interfaces 1 (4), 824-832

43 2009
Dental resins and degradable elastomers made from natural compounds

MA Gauthier, JE Gautro, G Giguere, K Metera

Program & Abstracts of the 4~(th) International Symposium on Engineering …

2009
Synthese funktioneller Polymere durch polymeranaloge Reaktionen

MA Gauthier, MI Gibson, HA Klok

Angewandte Chemie 121 (1), 50-60

56 2009
Synthesis of functional polymers by post‐polymerization modification

MA Gauthier, MI Gibson, HA Klok

Angewandte Chemie International Edition 48 (1), 48-58

1108 2009
Peptide/protein–polymer conjugates: synthetic strategies and design concepts

MA Gauthier, HA Klok

Chemical Communications, 2591-2611

496 2008
Bile acids as constituents for dental composites: in vitro cytotoxicity of (meth) acrylate and other ester derivatives of bile acids

MA Gauthier, P Simard, Z Zhang, XX Zhu

Journal of The Royal Society Interface 4 (17), 1145-1150

37 2007
New Polymer Materials for Dental Applications

M Gauthier

Abstracts of the Third International Symposium on Engineering Plastics

2007
Large uniform-sized polymer beads for use as solid-phase supports prepared by ascension polymerization

XX Zhu, JH Zhang, M Gauthier, JT Luo, FS Meng, F Brisse

Journal of Combinatorial Chemistry 8 (1), 79-84

8 2006
Développement et caractérisation de matériaux dentaires hautement performants

MA Gauthier

2 2006
A new method for quantifying the intensity of the C= C band of dimethacrylate dental monomers in their FTIR and Raman spectra

MA Gauthier, I Stangel, TH Ellis, XX Zhu

Biomaterials 26 (33), 6440-6448

113 2005
Dental materials containing bile acid derivatives

MA Gauthier, I Stangel, TH Ellis, XX Zhu

ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 230, U4095-U4095

2005
Oxygen inhibition in dental resins

MA Gauthier, I Stangel, TH Ellis, XX Zhu

Journal of dental research 84 (8), 725-729

259 2005
Thiol-functionalized polymeric micelles: from molecular recognition to improved mucoadhesion

MH Dufresne, MA Gauthier, JC Leroux

Bioconjugate chemistry 16 (4), 1027-1033

74 2005
Degree of crosslinking and mechanical properties of crosslinked poly (vinyl alcohol) beads for use in solid-phase organic synthesis

MA Gauthier, J Luo, D Calvet, C Ni, XX Zhu, M Garon, MD Buschmann

Polymer 45 (24), 8201-8210

78 2004
Confocal Raman micro-spectroscopic study of monomer conversion of dental resins.

MA Gauthier, TH Ellis, I Stangel

JOURNAL OF DENTAL RESEARCH 81, A84-A84

3 2002