
Immune system disturbances
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According to the World Health Organization (WHO), infectious diseases affect more than 300 million people a year and are responsible for about 17 million deaths a year. Infectious diseases are the third leading cause of death in developed countries.
An increasing number of infectious strains are becoming resistant to antiviral drugs and antibiotics. The re-emergence of infectious diseases that were thought to be under control, such as tuberculosis, is another challenge in the fight against these diseases.
A better understanding of the immune system and how infectious agents interact with it will help identify new ways to prevent and control these diseases. Our research teams are also working to reduce the emergence of new infectious diseases related to human and animal activities.
Host–pathogen interactions
To improve our understanding of host–pathogen interactions, we must characterize these interactions at the molecular level (protein–protein interactions, structure–function relationships, virulence factors) and at the cellular level (trafficking, transcriptional and functional regulation).
Immune response functions and regulation
The immune system plays an important role in distinguishing between the self and the non-self in organ transplants, for example. Our research teams are therefore studying regulatory mechanisms such as tolerance, immunosurveillance, and inflammatory and antimicrobial responses, as well as pathologies associated with the disruption of these functions
Infectious diseases and health
Food-borne diseases, animal health, and zoonotic risks associated with agricultural animals are a public health problem. Developing technology to detect, diagnose, and eliminate contaminants responsible for these infectious diseases is also part of our research.
Immune system disturbances
Virology and hepatology
Biochemistry
Dengue virus
Cellular and molecular characterization
Identification and characterization of bacterial genes affecting humans, poultry and pigs
Hematopoiesis and stem cells
Cellular and molecular characterization
Antiviral and antitumor immune responses
Medicinal chemistry
Cancer epidemiology
Molecular virology and viral pathogenesis
Virus-host interactions
Immunology of infectious diseases
Viral neurological disease
Immunology and Virology
Genomic bacteriology and evolution